Literatur:


1. Bredt DS: Endogenous nitric oxide synthesis: Biological functions and pathophysiology. Free Rad Res 31, 577-596

2. Tsikas D, Böger RH, Sandmann J, Bode-Böger SM, Frölich JC: Endogenous nitric oxide synthase inhibitors are responsible for the L-arginine paradox. FEBS Lett 478, 1-3 (2000)

3. Alderton WK, Cooper CE, Knowles G: Nitric oxide synthases: Structure, function and inhibition. Biochem J 357, 593-615 (2001)

4. Paolocci N, Saavedra WF, Miranda KM, Martignani C, Isoda T, Hare JM, Espey MG, Fukuto JM, Feelisch M, Wink DA: Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling. PNAS 98, 10463-10468 (2001)

5. Reid MB: Role of nitric oxide in skeletal muscle: synthesis, distribution and functional importance. Acta Physiol Scand 162, 401-409 (1998)

6. Higaki Y, Hirshman MF, Fujii N, Goodyear LJ: Nitric oxide increases glucose uptake through a mechanism that is distinct from the insulin and contraction pathways in rat skeletal muscle. Diabetes 50, 241-247 (2001)

7. Kapur S, Picard F, Perreault M, Deshaies Y, Marette A: Nitric oxide: A new player in the modulaton of energy metabolism. Int J Obesity 24, S36-S40 (2000)

8. Bloodsworth A, O`Donell VB, Freeman BA: Nitric oxide regulation of free radical- and enzyme-mediated lipid and lipoprotein oxidation. Arteriosclr Thromb Vasc Biol 20, 1707-1715 (2000)

9. Rubbo H, Radi R, Anselmi D, Kirk M, Barnes S, Butler J, Eiserich JP, Freeman BA: Nitric oxide reaction with lipid peroxyl radicals spares a -tocopherol during lipid oxidation. J Biol Chem 275, 10812-10818 (2000)

10. Tsuda T, Kato Y, Osawa T: Mechanism for the peroxynitrite scavening activity by anthocyanins. FEBS Lett 484, 207-210 (2000)

11. Heijnen CGM, Haenen GRMM, Vekemans JAJM, Bast A: Peroxynitrite scavening of flavonoids: structure activity relationship. Env Toxicol Pharmacol 10, 199-206 (2001)

12. Kirsch M, de Groot H: Ascorbate is a potent antioxidant against peroxynitrite-induced oxidation reactions. J Biol Chem 275, 16702-16708 (2000)

13. Klatt P, Lamas S: Regulation of protein function by S-glutathiolation in response to oxidative and nitrosative stress. Eur J Biochem 276, 4928-4944 (2000)

14. Freedman JE, Li L, Sauter R, Keaney JF:a -Tocopherol and protein kinase C inhibition enhance platelet-derived nitric oxide release. FASEB J 14, 2377-2379 (2000)

15. Mutus B, Rabini RA, Franceschi C, Paolisso G, Rizzo MR, Ragno E, Rappelli A, Braconi M, Mazzanti L: Cellular resistance to homocysteine: A key for longevity? Atherosclerosis 152, 527-528 (2000)

16. Sjöholm A, Berggren P-O, Cooney RV:g -Tocopherol partially protects insulin-secreting cells against functional inhibition by nitric oxide. Biochem Biophys Res Com 277, 334-340 (2000)

17. Nakazawa H, Fukuyama N, Takizawa S, Tsuji C, Yoshitake M, Ishida H: Nitrotyrosine formation and ist role in various pathological conditions. Free Rad Res 33, 771-784 (2000)

18. Oldreive C, Rice-Evans C: The mechanism for nitration and nitrotyrosine formation in vitro and in vivo: Impact of diet. Free Rad Res 35, 215-231 (2001)

19. Sawa T, Akaike T, Maeda H: Tyrosine nitration by peroxynitrite formed from nitric oxide and superoxide generated by xanthine oxidase. J Biol Chem 275, 32467-32474 (2000)

20. Sawa T, Akaike T, Maeda H: Tyrosine nitration by peroxynitrite formed from nitric oxide and superoxide generated by xanthine oxidase. J Biol Chem 275, 32467-32474 (2000)

21. Reiter CD, Teng R-J, Beckman JS: Superoxide reacts with nitric oxide to nitrate tyrosine at physiological pH via peroxynitrite. J Biol Chem 275, 32460-32466 (2000)

22. Pfeiffer S, Lass A, Schmidt K, Mayer B: Protein tyrosine nitration in cytokine-activated murine macrophages. J Biol Chem 276, 34051-34058 (2001)

23. Zhang H, Joseph J, Feix J, Hogg N, Kalyanaraman B: Nitration and oxidation of a hydrophobic tyrosine probe by peroxynitrite in membranes: Comparison with nitration and oxidation of tyrosine by peroxynitrite in aqueous solution. Biochemistry 40, 7675-7686 (2001)

24. Guermonprez L, Ducrocq C, Gaudery-Talarmain YM: Inhibition of acetylcholine synthesis and tyrosine nitration induced by peroxynitrite are differentially prevented by antioxidants. Molecular Pharmacol 60, 838-846 (2001)

25. Goumas G, Tentolouris C, Tousoulis D, Stefanadis C, Toutouzas P: Therapeutic modification of the L-arginine-eNOS pathway in cardiovascular diseases.

Artherosclerosis 154, 255-267 (2001)

26. Noguchi T, Sagami I, Daff S, Shimizu T: Important role of tetrahydrobiopterin in NO complex formation and interdomain electron transfer in neuronal nitric-oxide synthase. Biochem Biophys Res Com 282, 1092-1097 (2001)

27. Ohshima H, Friesen M, Brouet I, Bartsch H: Nitrotyrosine as a new marker for endogenous nitrosation and nitration of proteins. Food Chem Toxicol 28, 647-652 (1990)

28. Krainev AG, Williams TD, Bigelow DJ: Enzymatic reduction of 3-nitrotyrosine generates superoxide. Chem Res Toxicol 11, 495-502 (1998)

29. Kamisaki Y, Wada K, Bian K, Balabanli B, Davis K, Martin E, Behbod F, Lee Y-C, Murad F: An activity in rat tissues modifies nitrotyrosine-containing proteins. PNAS 95, 11584-11589 (1998)

30. Greenacre SAB, Ischiropoulos H: Tyrosine nitration: Localisation, quantification, consequences for protein function and signal transduction. Free Rad Res 34, 541-581 (2001)

31. Leeuwenburgh C, Hardy MM, Hazen SL, Wagner P, Oh-ishi S, Steinbrecher UP, Heinecke JW: Reactive nitrogen intermediates promote low density lipoprotein oxidation in human atherosclerotic intima. J Biol Chem 272, 1433-1436 (1997)

32. Matata BM, Sosnowski AW, Galinanes M: Off-pump bypass graft operation significantly reduces oxidative stress and inflammation. Ann Thoracic Surgery 69, 785-791 (2000)

33. Jiang H, Balazy M: Detection of 3-nitrotyrosine in human platelets exposed to peroxynitrite by a new gas chromatography/mass spectrometry assay. Nitric Oxide 2, 350-359 (1998)

34. Petruzzelli S, Puntoni R, Mimotti P, Pulera N, Baliva F, Fornai E, Giuntini C: Plasma 3-nitrotyrosine in cigarette smokers. Am J Respiratory and Critical Care Med 156, 1902-1907 (1997)

35. Pignatelli B, Li C-Q, Boffetta P, Chen Q, Ahrens W, Nyberg F, Mukeria A, Bruske-Hohlfeld I, Fortes C, Constantinescu V, Ischiropoulos H, Ohshima H: Nitrated and oxidized plasma proteins in smokers and lung cancer patients. Cancer Res 61, 778-784 (2001)

36. MacMillan-Crow LA, Greendorfer JS, Vickers SM, Thompson JA: Tyrosine nitration of c-SRC tyrosine kinase in human pancreatic ductal adenocarcinoma. Arch Biochem Biophys 377, 350-356 (2000)

37. Oldreive C, Bradley N, Bruckdorfer R, Rice-Evans C: Lack of influence of dietary nitrate/nitrite on plasma nitrotyrosine levels measured using a competitive inhibition of binding ELISA assay. Free Rad Res 35, 377-386 (2001)

38. Napoli C, Ignarro LJ: Nitric oxide and atherosclerosis. Biol and Chem 5, 88-97 (2001)

39. Ekmekcioglu S, Ellerhorst J, Smid CM, Prieto VG, Munsell M, Buzaid AC, Grimm EA: Inducible nitric oxide synthase and nitrotyrosine in human metastatic melanoma tumors correlate with poor survival. Clin Cancer Res 6, 4768-4775 (2000)

40. Cobbs CS, Samanta M, Harkins LE, Gillespie GY, Merrick BA, MacMillan-Crow LA: Evidence for peroxynitrite-mediated modifications to p53 in human gliomas: Possible functional consequences. Arch Biochem Biophys 394, 167-172 (2001)

41. Tokimoto T, Shinagawa K: Nitric oxide generation in aqueous solutions of cigarette smoke and approaches to its origin. Biol Chem 382, 1613-1619 (2001)



Literatur:


1. Bredt DS: Endogenous nitric oxide synthesis: Biological functions and pathophysiology. Free Rad Res 31, 577-596

2. Tsikas D, Böger RH, Sandmann J, Bode-Böger SM, Frölich JC: Endogenous nitric oxide synthase inhibitors are responsible for the L-arginine paradox. FEBS Lett 478, 1-3 (2000)

3. Alderton WK, Cooper CE, Knowles G: Nitric oxide synthases: Structure, function and inhibition. Biochem J 357, 593-615 (2001)

4. Paolocci N, Saavedra WF, Miranda KM, Martignani C, Isoda T, Hare JM, Espey MG, Fukuto JM, Feelisch M, Wink DA: Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling. PNAS 98, 10463-10468 (2001)

5. Reid MB: Role of nitric oxide in skeletal muscle: synthesis, distribution and functional importance. Acta Physiol Scand 162, 401-409 (1998)

6. Higaki Y, Hirshman MF, Fujii N, Goodyear LJ: Nitric oxide increases glucose uptake through a mechanism that is distinct from the insulin and contraction pathways in rat skeletal muscle. Diabetes 50, 241-247 (2001)

7. Kapur S, Picard F, Perreault M, Deshaies Y, Marette A: Nitric oxide: A new player in the modulaton of energy metabolism. Int J Obesity 24, S36-S40 (2000)

8. Bloodsworth A, O`Donell VB, Freeman BA: Nitric oxide regulation of free radical- and enzyme-mediated lipid and lipoprotein oxidation. Arteriosclr Thromb Vasc Biol 20, 1707-1715 (2000)

9. Rubbo H, Radi R, Anselmi D, Kirk M, Barnes S, Butler J, Eiserich JP, Freeman BA: Nitric oxide reaction with lipid peroxyl radicals spares a -tocopherol during lipid oxidation. J Biol Chem 275, 10812-10818 (2000)

10. Tsuda T, Kato Y, Osawa T: Mechanism for the peroxynitrite scavening activity by anthocyanins. FEBS Lett 484, 207-210 (2000)

11. Heijnen CGM, Haenen GRMM, Vekemans JAJM, Bast A: Peroxynitrite scavening of flavonoids: structure activity relationship. Env Toxicol Pharmacol 10, 199-206 (2001)

12. Kirsch M, de Groot H: Ascorbate is a potent antioxidant against peroxynitrite-induced oxidation reactions. J Biol Chem 275, 16702-16708 (2000)

13. Klatt P, Lamas S: Regulation of protein function by S-glutathiolation in response to oxidative and nitrosative stress. Eur J Biochem 276, 4928-4944 (2000)

14. Freedman JE, Li L, Sauter R, Keaney JF:a -Tocopherol and protein kinase C inhibition enhance platelet-derived nitric oxide release. FASEB J 14, 2377-2379 (2000)

15. Mutus B, Rabini RA, Franceschi C, Paolisso G, Rizzo MR, Ragno E, Rappelli A, Braconi M, Mazzanti L: Cellular resistance to homocysteine: A key for longevity? Atherosclerosis 152, 527-528 (2000)

16. Sjöholm A, Berggren P-O, Cooney RV:g -Tocopherol partially protects insulin-secreting cells against functional inhibition by nitric oxide. Biochem Biophys Res Com 277, 334-340 (2000)

17. Nakazawa H, Fukuyama N, Takizawa S, Tsuji C, Yoshitake M, Ishida H: Nitrotyrosine formation and ist role in various pathological conditions. Free Rad Res 33, 771-784 (2000)

18. Oldreive C, Rice-Evans C: The mechanism for nitration and nitrotyrosine formation in vitro and in vivo: Impact of diet. Free Rad Res 35, 215-231 (2001)

19. Sawa T, Akaike T, Maeda H: Tyrosine nitration by peroxynitrite formed from nitric oxide and superoxide generated by xanthine oxidase. J Biol Chem 275, 32467-32474 (2000)

20. Sawa T, Akaike T, Maeda H: Tyrosine nitration by peroxynitrite formed from nitric oxide and superoxide generated by xanthine oxidase. J Biol Chem 275, 32467-32474 (2000)

21. Reiter CD, Teng R-J, Beckman JS: Superoxide reacts with nitric oxide to nitrate tyrosine at physiological pH via peroxynitrite. J Biol Chem 275, 32460-32466 (2000)

22. Pfeiffer S, Lass A, Schmidt K, Mayer B: Protein tyrosine nitration in cytokine-activated murine macrophages. J Biol Chem 276, 34051-34058 (2001)

23. Zhang H, Joseph J, Feix J, Hogg N, Kalyanaraman B: Nitration and oxidation of a hydrophobic tyrosine probe by peroxynitrite in membranes: Comparison with nitration and oxidation of tyrosine by peroxynitrite in aqueous solution. Biochemistry 40, 7675-7686 (2001)

24. Guermonprez L, Ducrocq C, Gaudery-Talarmain YM: Inhibition of acetylcholine synthesis and tyrosine nitration induced by peroxynitrite are differentially prevented by antioxidants. Molecular Pharmacol 60, 838-846 (2001)

25. Goumas G, Tentolouris C, Tousoulis D, Stefanadis C, Toutouzas P: Therapeutic modification of the L-arginine-eNOS pathway in cardiovascular diseases.

Artherosclerosis 154, 255-267 (2001)

26. Noguchi T, Sagami I, Daff S, Shimizu T: Important role of tetrahydrobiopterin in NO complex formation and interdomain electron transfer in neuronal nitric-oxide synthase. Biochem Biophys Res Com 282, 1092-1097 (2001)

27. Ohshima H, Friesen M, Brouet I, Bartsch H: Nitrotyrosine as a new marker for endogenous nitrosation and nitration of proteins. Food Chem Toxicol 28, 647-652 (1990)

28. Krainev AG, Williams TD, Bigelow DJ: Enzymatic reduction of 3-nitrotyrosine generates superoxide. Chem Res Toxicol 11, 495-502 (1998)

29. Kamisaki Y, Wada K, Bian K, Balabanli B, Davis K, Martin E, Behbod F, Lee Y-C, Murad F: An activity in rat tissues modifies nitrotyrosine-containing proteins. PNAS 95, 11584-11589 (1998)

30. Greenacre SAB, Ischiropoulos H: Tyrosine nitration: Localisation, quantification, consequences for protein function and signal transduction. Free Rad Res 34, 541-581 (2001)

31. Leeuwenburgh C, Hardy MM, Hazen SL, Wagner P, Oh-ishi S, Steinbrecher UP, Heinecke JW: Reactive nitrogen intermediates promote low density lipoprotein oxidation in human atherosclerotic intima. J Biol Chem 272, 1433-1436 (1997)

32. Matata BM, Sosnowski AW, Galinanes M: Off-pump bypass graft operation significantly reduces oxidative stress and inflammation. Ann Thoracic Surgery 69, 785-791 (2000)

33. Jiang H, Balazy M: Detection of 3-nitrotyrosine in human platelets exposed to peroxynitrite by a new gas chromatography/mass spectrometry assay. Nitric Oxide 2, 350-359 (1998)

34. Petruzzelli S, Puntoni R, Mimotti P, Pulera N, Baliva F, Fornai E, Giuntini C: Plasma 3-nitrotyrosine in cigarette smokers. Am J Respiratory and Critical Care Med 156, 1902-1907 (1997)

35. Pignatelli B, Li C-Q, Boffetta P, Chen Q, Ahrens W, Nyberg F, Mukeria A, Bruske-Hohlfeld I, Fortes C, Constantinescu V, Ischiropoulos H, Ohshima H: Nitrated and oxidized plasma proteins in smokers and lung cancer patients. Cancer Res 61, 778-784 (2001)

36. MacMillan-Crow LA, Greendorfer JS, Vickers SM, Thompson JA: Tyrosine nitration of c-SRC tyrosine kinase in human pancreatic ductal adenocarcinoma. Arch Biochem Biophys 377, 350-356 (2000)

37. Oldreive C, Bradley N, Bruckdorfer R, Rice-Evans C: Lack of influence of dietary nitrate/nitrite on plasma nitrotyrosine levels measured using a competitive inhibition of binding ELISA assay. Free Rad Res 35, 377-386 (2001)

38. Napoli C, Ignarro LJ: Nitric oxide and atherosclerosis. Biol and Chem 5, 88-97 (2001)

39. Ekmekcioglu S, Ellerhorst J, Smid CM, Prieto VG, Munsell M, Buzaid AC, Grimm EA: Inducible nitric oxide synthase and nitrotyrosine in human metastatic melanoma tumors correlate with poor survival. Clin Cancer Res 6, 4768-4775 (2000)

40. Cobbs CS, Samanta M, Harkins LE, Gillespie GY, Merrick BA, MacMillan-Crow LA: Evidence for peroxynitrite-mediated modifications to p53 in human gliomas: Possible functional consequences. Arch Biochem Biophys 394, 167-172 (2001)

41. Tokimoto T, Shinagawa K: Nitric oxide generation in aqueous solutions of cigarette smoke and approaches to its origin. Biol Chem 382, 1613-1619 (2001)

(EU 04/2002, S. 133 ff.) Schmandke, H.: 3-Nitro-L-tyrosin – Biomarker für nitrosativen Stress?

Literatur:

1. Bredt DS: Endogenous nitric oxide synthesis: Biological functions and pathophysiology. Free Rad Res 31, 577-596

2. Tsikas D, Böger RH, Sandmann J, Bode-Böger SM, Frölich JC: Endogenous nitric oxide synthase inhibitors are responsible for the L-arginine paradox. FEBS Lett 478, 1-3 (2000)

3. Alderton WK, Cooper CE, Knowles G: Nitric oxide synthases: Structure, function and inhibition. Biochem J 357, 593-615 (2001)

4. Paolocci N, Saavedra WF, Miranda KM, Martignani C, Isoda T, Hare JM, Espey MG, Fukuto JM, Feelisch M, Wink DA: Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling. PNAS 98, 10463-10468 (2001)

5. Reid MB: Role of nitric oxide in skeletal muscle: synthesis, distribution and functional importance. Acta Physiol Scand 162, 401-409 (1998)

6. Higaki Y, Hirshman MF, Fujii N, Goodyear LJ: Nitric oxide increases glucose uptake through a mechanism that is distinct from the insulin and contraction pathways in rat skeletal muscle. Diabetes 50, 241-247 (2001)

7. Kapur S, Picard F, Perreault M, Deshaies Y, Marette A: Nitric oxide: A new player in the modulaton of energy metabolism. Int J Obesity 24, S36-S40 (2000)

8. Bloodsworth A, O`Donell VB, Freeman BA: Nitric oxide regulation of free radical- and enzyme-mediated lipid and lipoprotein oxidation. Arteriosclr Thromb Vasc Biol 20, 1707-1715 (2000)

9. Rubbo H, Radi R, Anselmi D, Kirk M, Barnes S, Butler J, Eiserich JP, Freeman BA: Nitric oxide reaction with lipid peroxyl radicals spares a -tocopherol during lipid oxidation. J Biol Chem 275, 10812-10818 (2000)

10. Tsuda T, Kato Y, Osawa T: Mechanism for the peroxynitrite scavening activity by anthocyanins. FEBS Lett 484, 207-210 (2000)

11. Heijnen CGM, Haenen GRMM, Vekemans JAJM, Bast A: Peroxynitrite scavening of flavonoids: structure activity relationship. Env Toxicol Pharmacol 10, 199-206 (2001)

12. Kirsch M, de Groot H: Ascorbate is a potent antioxidant against peroxynitrite-induced oxidation reactions. J Biol Chem 275, 16702-16708 (2000)

13. Klatt P, Lamas S: Regulation of protein function by S-glutathiolation in response to oxidative and nitrosative stress. Eur J Biochem 276, 4928-4944 (2000)

14. Freedman JE, Li L, Sauter R, Keaney JF:a -Tocopherol and protein kinase C inhibition enhance platelet-derived nitric oxide release. FASEB J 14, 2377-2379 (2000)

15. Mutus B, Rabini RA, Franceschi C, Paolisso G, Rizzo MR, Ragno E, Rappelli A, Braconi M, Mazzanti L: Cellular resistance to homocysteine: A key for longevity? Atherosclerosis 152, 527-528 (2000)

16. Sjöholm A, Berggren P-O, Cooney RV:g -Tocopherol partially protects insulin-secreting cells against functional inhibition by nitric oxide. Biochem Biophys Res Com 277, 334-340 (2000)

17. Nakazawa H, Fukuyama N, Takizawa S, Tsuji C, Yoshitake M, Ishida H: Nitrotyrosine formation and ist role in various pathological conditions. Free Rad Res 33, 771-784 (2000)

18. Oldreive C, Rice-Evans C: The mechanism for nitration and nitrotyrosine formation in vitro and in vivo: Impact of diet. Free Rad Res 35, 215-231 (2001)

19. Sawa T, Akaike T, Maeda H: Tyrosine nitration by peroxynitrite formed from nitric oxide and superoxide generated by xanthine oxidase. J Biol Chem 275, 32467-32474 (2000)

20. Sawa T, Akaike T, Maeda H: Tyrosine nitration by peroxynitrite formed from nitric oxide and superoxide generated by xanthine oxidase. J Biol Chem 275, 32467-32474 (2000)

21. Reiter CD, Teng R-J, Beckman JS: Superoxide reacts with nitric oxide to nitrate tyrosine at physiological pH via peroxynitrite. J Biol Chem 275, 32460-32466 (2000)

22. Pfeiffer S, Lass A, Schmidt K, Mayer B: Protein tyrosine nitration in cytokine-activated murine macrophages. J Biol Chem 276, 34051-34058 (2001)

23. Zhang H, Joseph J, Feix J, Hogg N, Kalyanaraman B: Nitration and oxidation of a hydrophobic tyrosine probe by peroxynitrite in membranes: Comparison with nitration and oxidation of tyrosine by peroxynitrite in aqueous solution. Biochemistry 40, 7675-7686 (2001)

24. Guermonprez L, Ducrocq C, Gaudery-Talarmain YM: Inhibition of acetylcholine synthesis and tyrosine nitration induced by peroxynitrite are differentially prevented by antioxidants. Molecular Pharmacol 60, 838-846 (2001)

25. Goumas G, Tentolouris C, Tousoulis D, Stefanadis C, Toutouzas P: Therapeutic modification of the L-arginine-eNOS pathway in cardiovascular diseases.

Artherosclerosis 154, 255-267 (2001)

26. Noguchi T, Sagami I, Daff S, Shimizu T: Important role of tetrahydrobiopterin in NO complex formation and interdomain electron transfer in neuronal nitric-oxide synthase. Biochem Biophys Res Com 282, 1092-1097 (2001)

27. Ohshima H, Friesen M, Brouet I, Bartsch H: Nitrotyrosine as a new marker for endogenous nitrosation and nitration of proteins. Food Chem Toxicol 28, 647-652 (1990)

28. Krainev AG, Williams TD, Bigelow DJ: Enzymatic reduction of 3-nitrotyrosine generates superoxide. Chem Res Toxicol 11, 495-502 (1998)

29. Kamisaki Y, Wada K, Bian K, Balabanli B, Davis K, Martin E, Behbod F, Lee Y-C, Murad F: An activity in rat tissues modifies nitrotyrosine-containing proteins. PNAS 95, 11584-11589 (1998)

30. Greenacre SAB, Ischiropoulos H: Tyrosine nitration: Localisation, quantification, consequences for protein function and signal transduction. Free Rad Res 34, 541-581 (2001)

31. Leeuwenburgh C, Hardy MM, Hazen SL, Wagner P, Oh-ishi S, Steinbrecher UP, Heinecke JW: Reactive nitrogen intermediates promote low density lipoprotein oxidation in human atherosclerotic intima. J Biol Chem 272, 1433-1436 (1997)

32. Matata BM, Sosnowski AW, Galinanes M: Off-pump bypass graft operation significantly reduces oxidative stress and inflammation. Ann Thoracic Surgery 69, 785-791 (2000)

33. Jiang H, Balazy M: Detection of 3-nitrotyrosine in human platelets exposed to peroxynitrite by a new gas chromatography/mass spectrometry assay. Nitric Oxide 2, 350-359 (1998)

34. Petruzzelli S, Puntoni R, Mimotti P, Pulera N, Baliva F, Fornai E, Giuntini C: Plasma 3-nitrotyrosine in cigarette smokers. Am J Respiratory and Critical Care Med 156, 1902-1907 (1997)

35. Pignatelli B, Li C-Q, Boffetta P, Chen Q, Ahrens W, Nyberg F, Mukeria A, Bruske-Hohlfeld I, Fortes C, Constantinescu V, Ischiropoulos H, Ohshima H: Nitrated and oxidized plasma proteins in smokers and lung cancer patients. Cancer Res 61, 778-784 (2001)

36. MacMillan-Crow LA, Greendorfer JS, Vickers SM, Thompson JA: Tyrosine nitration of c-SRC tyrosine kinase in human pancreatic ductal adenocarcinoma. Arch Biochem Biophys 377, 350-356 (2000)

37. Oldreive C, Bradley N, Bruckdorfer R, Rice-Evans C: Lack of influence of dietary nitrate/nitrite on plasma nitrotyrosine levels measured using a competitive inhibition of binding ELISA assay. Free Rad Res 35, 377-386 (2001)

38. Napoli C, Ignarro LJ: Nitric oxide and atherosclerosis. Biol and Chem 5, 88-97 (2001)

39. Ekmekcioglu S, Ellerhorst J, Smid CM, Prieto VG, Munsell M, Buzaid AC, Grimm EA: Inducible nitric oxide synthase and nitrotyrosine in human metastatic melanoma tumors correlate with poor survival. Clin Cancer Res 6, 4768-4775 (2000)

40. Cobbs CS, Samanta M, Harkins LE, Gillespie GY, Merrick BA, MacMillan-Crow LA: Evidence for peroxynitrite-mediated modifications to p53 in human gliomas: Possible functional consequences. Arch Biochem Biophys 394, 167-172 (2001)

41. Tokimoto T, Shinagawa K: Nitric oxide generation in aqueous solutions of cigarette smoke and approaches to its origin. Biol Chem 382, 1613-1619 (2001)

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Veröffentlicht: 05.04.2002

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