Literatur:    


1. Riordan, J.; Vallee, B.: Structure and function of zinc metalloenzymes; ; In: Prasad, A.; Oberleas, D. : Trace elements in human health and disease. 1- Zinc and cooper. New York, Academic Press, (1976), 227-256

2. Prasad, A.S.: Zinc: an overview. Nutrition. 11 (1995), 93-99

3. Fabris, N.; Mocchegiani, E.: Zinc, human diseases and aging. Aging Clin Exp Res 7 (1995), 77-93

4. Moynahan, E.: Acrodermitis enteropathica: a lethal inherited human zinc-deficiency disorder. Lancet 2 (1974), 399-400

5. Sandstead, H.H.; Henriksen, L.K.; Greger, J.L.; Prasad, A.S.; Good, R.A.: Zinc nutriture in the elderly in relation to taste acuity, immune response, and wound healing. Am J Clin Nutr 36 (1982), 1046-1059

6. Abbasi, A.; Shetty, K.: Zinc: pathophysiological effects, deficiency status and effects of supplementation in elderly persons--an overview of the research. Z Gerontol Geriatr 32, Suppl 1 (1999), 75-79

7. Lansdown, A.B.: Zinc in the healing wound. Lancet 347 (1996), 706-707

8. Iwata, M.; Takebayashi, T.; Ohta, H.; Alcalde, R.E.; Itano, Y.; Matsumura, T.: Zinc accumulation and metallothionein gene expression in the proliferating epidermis during wound healing in mouse skin. Histochem Cell Biol 112 (1999), 283-290

9. Salgueiro, M.J.; Zubillaga, M.; Lysionek, A.; Cremaschi, G.; Goldman, C.G.; Caro, R.; De Paoli, T.; Hager, A.; Weill, R.; Boccio, J.: Zinc status and immune system relationship: a review. Biol Trace Elem Res 76 (2000), 193-205

10. Laditan, A.A.; Ette, S.I.: Plasma zinc and copper levels during the acute phase of protein-energy malnutrition (PEM) and after recovery. Trop Geogr Med 34 (1982), 77-80

11. Constantinidis, J.: The hypothesis of zinc deficiency in the pathogenesis of neurofibrillary tangles. Med Hypoth 35 (1991),319-323

12. Turnlund, J.; Durvin, N.; Costa, F.; Margen, S.: Stable isotope studies of zinc absorption and retension in young and elderly men. J Nutr 116 (1986), 1239-1247

13. Corwin, E.J.: Understanding cytokines. Part I: Physiology and mechanism of action. Biol Res Nurs 2 (2000), 30-40

14. Androsova, L.V.; Kushner, S.G.; Abramova, L.I.; Oleichik, I.V.; Egorova, M.: Interleukin level in endogenous depression. Zh Nevrol Psikhiatr Im S S Korsakova 101 (2001), 45-48

15. Mikova, O.; Yakimova, R.; Bosmans, E.; Kenis, G.; Maes, M.: Increased serum tumor necrosis factor alpha concentrations in major depression and multiple sclerosis. European Neuropsychopharmacology 11 (2001), 203-208

16. Fagiolo, U.; Cosarizza, A.; Sanctacaterina, S.: Increased cytokine production by peripheral blood mononuclear cells from healthy elderly. Ann NY Acad Sci 663 (1992), 490-493

17. Bonnefoy, M.; Coulon, L.; Bienvenu, J.; Boisson, R.C.; Rys, L.: Implication of cytokines in the aggravation of malnutrition and hypercatabolism in elderly patients with severe pressure sores. Age Ageing 24 (1995), 37-42

18. Melchiar, B.; Jandik, P.; Tichy, M.; Malir, F.; Mergancova, J.; Voboril, Z.: Urinary zinc excretion and acute phase response in cancer patients. Clin Investig 72 (1994), 1012-1014

19. Dantzer, R.: Cytokine-induced sickness behavior: where do we stand? Brain Behav Immun 15 (2001), 7-24

20. McWhiter, J.; Pennington, C.: Incidence and recognition of malnurtrition in hospitals. Nutr Hosp 308 (1994), 945-948

21. Potter, J.; Klipstein, K.; Reilly, J.; Robert, M.: The nutritional status and clinical course of acute admissions to a geriatric unit. Age ageing 24 (1995), 131-136

22. Sandström, B.: Dose dependence of zinc and manganese absorption in man. Proc Nutr Soc 51 (1992), 211-218

23. Sandström, B.; Cederblad, A.: Zinc absorption from composite meals. II. Influence of the main protein source. Am J Clin Nutr 33 (1980), 1778-1783

24. Wapnir, R.; Khani, D.; Bayne, M.; Lifshitz, F.: Absorption by the rat ileum: the effect of histidin and other low-molecular-weight ligands. J Nutr 113 (1983), 1434-1442

25. Sandström, B.; Arvidsson, B.; Cederbald, A.; Björn-Rasmussen, E.: Zinc absorption from composite meals. I. The significance of wheat extraction rate, zinc, calcium and protein content in meals based on bread. Am J Clin Nutr 33 (1980), 739-745

26. Monget, A.; Galan, P.; Presiosi, P.; Keller, H.; Bourgeois, C.: Micronutrient status in the elderly people. Internat J Vit Nutr Res 66 (1996), 71-76

27. Stafford, W.; Smith, R.; Lewis, S.; Henery, E.; Stephen, P.: A study of zinc status of elderly institutionalized patients. Age Ageing 17 (1996), 42-48

28. Meertens, L.; Solano, L.; Pena, E.: Zinc status evaluation in an elderly institutionalized population. Arch Latinoam Nutr. 47 (1997), 311-314

29. Morley, J.E.; Silver, A.J.: Nutritional issues in nursing home care. Ann Intern Med 123 (1995), 850-859

30. Worwag, M.; Classen, H.G.; Schumacher, E.: Prevalence of magnesium and zinc deficiencies in nursing home residents in Germany. Magnes Res 12 (1999), 181-189

31. Aggett, P.; Comerford, J.: Zinc and human health. Nutr Rev 53 (1995), 16-22

32. Fraker, P.J.; King, L.: Changes in regulation of lymphopoiesis and myelopoiesis in the zinc-deficient mouse. Nutr Rev 56 (1998), 65-69

33. Fraker, P.J.; King, L.E.; Laakko, T.; Vollmer, T.L.: The dynamic link between the integrity of the immune system and zinc status. J Nutr 130 (2000), 1399S-1406S

34. Souci, S.; Fachmann, W.; Kraut, H.: Die Zusammensetzung der Lebensmittel. Stuttgart, Wissenschaftliche Verlagsgesellschaft mbH (1989).

35. Roth, H.; Kirchgessner, M.: Diagnostik des Zinkmangels. Z Gerontol Geriat 32, Suppl 1 (1999), 55-64

36. Cousins, R.: Absorption, transport and hepatic metabolism of copper and zinc: special reference to metallothionein and ceruloplasmin. Physiol Rev 65 (1985), 238-309

37. Aggett, P.J.; Favier, A.: Zinc. Int J Vitam Nutr Res 63 (1993), 301-307

38. Andrews, M.; Gallagher-Allred, C.: The role of zinc in wound healing. Adv Wound Care 12 (1999), 137-138

39. Maes, M.; De Vos, N.; Demedts, P.; Wauters, A.; Neels, H.: Lower serum zinc in major depression in relation to changes in serum acute phase proteins. J Affect Disord 56 (1999), 189-194

40. Mocchegiani, E.; Muzzioli, M.; Giacconi, R.: Zinc and immunoresistance to infection in aging: new biological tools. Trends Pharmacol Sci. 21 (2000), 205-208

41. Rulon, L.L.; Robertson, J.D.; Lovell, M.A.; Deibel, M.A.; Ehmann, W.D.; Markesber, W.R.: Serum zinc levels and Alzheimer´s disease. Biol Trace Elem Res 75 (2000), 79-85

42. Mitrache, C.; Passweg, J.R.; Libura, J.; Petrikkos, L.; Seiler, W.O.; Gratwohl, A.; Staehelin, H.B.; Tichelli, A.: Anemia: an indicator for malnutrition in the elderly. Ann Hematol 80 (2001), 295-298 EU07/02



Literatur:    


1. Riordan, J.; Vallee, B.: Structure and function of zinc metalloenzymes; ; In: Prasad, A.; Oberleas, D. : Trace elements in human health and disease. 1- Zinc and cooper. New York, Academic Press, (1976), 227-256

2. Prasad, A.S.: Zinc: an overview. Nutrition. 11 (1995), 93-99

3. Fabris, N.; Mocchegiani, E.: Zinc, human diseases and aging. Aging Clin Exp Res 7 (1995), 77-93

4. Moynahan, E.: Acrodermitis enteropathica: a lethal inherited human zinc-deficiency disorder. Lancet 2 (1974), 399-400

5. Sandstead, H.H.; Henriksen, L.K.; Greger, J.L.; Prasad, A.S.; Good, R.A.: Zinc nutriture in the elderly in relation to taste acuity, immune response, and wound healing. Am J Clin Nutr 36 (1982), 1046-1059

6. Abbasi, A.; Shetty, K.: Zinc: pathophysiological effects, deficiency status and effects of supplementation in elderly persons--an overview of the research. Z Gerontol Geriatr 32, Suppl 1 (1999), 75-79

7. Lansdown, A.B.: Zinc in the healing wound. Lancet 347 (1996), 706-707

8. Iwata, M.; Takebayashi, T.; Ohta, H.; Alcalde, R.E.; Itano, Y.; Matsumura, T.: Zinc accumulation and metallothionein gene expression in the proliferating epidermis during wound healing in mouse skin. Histochem Cell Biol 112 (1999), 283-290

9. Salgueiro, M.J.; Zubillaga, M.; Lysionek, A.; Cremaschi, G.; Goldman, C.G.; Caro, R.; De Paoli, T.; Hager, A.; Weill, R.; Boccio, J.: Zinc status and immune system relationship: a review. Biol Trace Elem Res 76 (2000), 193-205

10. Laditan, A.A.; Ette, S.I.: Plasma zinc and copper levels during the acute phase of protein-energy malnutrition (PEM) and after recovery. Trop Geogr Med 34 (1982), 77-80

11. Constantinidis, J.: The hypothesis of zinc deficiency in the pathogenesis of neurofibrillary tangles. Med Hypoth 35 (1991),319-323

12. Turnlund, J.; Durvin, N.; Costa, F.; Margen, S.: Stable isotope studies of zinc absorption and retension in young and elderly men. J Nutr 116 (1986), 1239-1247

13. Corwin, E.J.: Understanding cytokines. Part I: Physiology and mechanism of action. Biol Res Nurs 2 (2000), 30-40

14. Androsova, L.V.; Kushner, S.G.; Abramova, L.I.; Oleichik, I.V.; Egorova, M.: Interleukin level in endogenous depression. Zh Nevrol Psikhiatr Im S S Korsakova 101 (2001), 45-48

15. Mikova, O.; Yakimova, R.; Bosmans, E.; Kenis, G.; Maes, M.: Increased serum tumor necrosis factor alpha concentrations in major depression and multiple sclerosis. European Neuropsychopharmacology 11 (2001), 203-208

16. Fagiolo, U.; Cosarizza, A.; Sanctacaterina, S.: Increased cytokine production by peripheral blood mononuclear cells from healthy elderly. Ann NY Acad Sci 663 (1992), 490-493

17. Bonnefoy, M.; Coulon, L.; Bienvenu, J.; Boisson, R.C.; Rys, L.: Implication of cytokines in the aggravation of malnutrition and hypercatabolism in elderly patients with severe pressure sores. Age Ageing 24 (1995), 37-42

18. Melchiar, B.; Jandik, P.; Tichy, M.; Malir, F.; Mergancova, J.; Voboril, Z.: Urinary zinc excretion and acute phase response in cancer patients. Clin Investig 72 (1994), 1012-1014

19. Dantzer, R.: Cytokine-induced sickness behavior: where do we stand? Brain Behav Immun 15 (2001), 7-24

20. McWhiter, J.; Pennington, C.: Incidence and recognition of malnurtrition in hospitals. Nutr Hosp 308 (1994), 945-948

21. Potter, J.; Klipstein, K.; Reilly, J.; Robert, M.: The nutritional status and clinical course of acute admissions to a geriatric unit. Age ageing 24 (1995), 131-136

22. Sandström, B.: Dose dependence of zinc and manganese absorption in man. Proc Nutr Soc 51 (1992), 211-218

23. Sandström, B.; Cederblad, A.: Zinc absorption from composite meals. II. Influence of the main protein source. Am J Clin Nutr 33 (1980), 1778-1783

24. Wapnir, R.; Khani, D.; Bayne, M.; Lifshitz, F.: Absorption by the rat ileum: the effect of histidin and other low-molecular-weight ligands. J Nutr 113 (1983), 1434-1442

25. Sandström, B.; Arvidsson, B.; Cederbald, A.; Björn-Rasmussen, E.: Zinc absorption from composite meals. I. The significance of wheat extraction rate, zinc, calcium and protein content in meals based on bread. Am J Clin Nutr 33 (1980), 739-745

26. Monget, A.; Galan, P.; Presiosi, P.; Keller, H.; Bourgeois, C.: Micronutrient status in the elderly people. Internat J Vit Nutr Res 66 (1996), 71-76

27. Stafford, W.; Smith, R.; Lewis, S.; Henery, E.; Stephen, P.: A study of zinc status of elderly institutionalized patients. Age Ageing 17 (1996), 42-48

28. Meertens, L.; Solano, L.; Pena, E.: Zinc status evaluation in an elderly institutionalized population. Arch Latinoam Nutr. 47 (1997), 311-314

29. Morley, J.E.; Silver, A.J.: Nutritional issues in nursing home care. Ann Intern Med 123 (1995), 850-859

30. Worwag, M.; Classen, H.G.; Schumacher, E.: Prevalence of magnesium and zinc deficiencies in nursing home residents in Germany. Magnes Res 12 (1999), 181-189

31. Aggett, P.; Comerford, J.: Zinc and human health. Nutr Rev 53 (1995), 16-22

32. Fraker, P.J.; King, L.: Changes in regulation of lymphopoiesis and myelopoiesis in the zinc-deficient mouse. Nutr Rev 56 (1998), 65-69

33. Fraker, P.J.; King, L.E.; Laakko, T.; Vollmer, T.L.: The dynamic link between the integrity of the immune system and zinc status. J Nutr 130 (2000), 1399S-1406S

34. Souci, S.; Fachmann, W.; Kraut, H.: Die Zusammensetzung der Lebensmittel. Stuttgart, Wissenschaftliche Verlagsgesellschaft mbH (1989).

35. Roth, H.; Kirchgessner, M.: Diagnostik des Zinkmangels. Z Gerontol Geriat 32, Suppl 1 (1999), 55-64

36. Cousins, R.: Absorption, transport and hepatic metabolism of copper and zinc: special reference to metallothionein and ceruloplasmin. Physiol Rev 65 (1985), 238-309

37. Aggett, P.J.; Favier, A.: Zinc. Int J Vitam Nutr Res 63 (1993), 301-307

38. Andrews, M.; Gallagher-Allred, C.: The role of zinc in wound healing. Adv Wound Care 12 (1999), 137-138

39. Maes, M.; De Vos, N.; Demedts, P.; Wauters, A.; Neels, H.: Lower serum zinc in major depression in relation to changes in serum acute phase proteins. J Affect Disord 56 (1999), 189-194

40. Mocchegiani, E.; Muzzioli, M.; Giacconi, R.: Zinc and immunoresistance to infection in aging: new biological tools. Trends Pharmacol Sci. 21 (2000), 205-208

41. Rulon, L.L.; Robertson, J.D.; Lovell, M.A.; Deibel, M.A.; Ehmann, W.D.; Markesber, W.R.: Serum zinc levels and Alzheimer´s disease. Biol Trace Elem Res 75 (2000), 79-85

42. Mitrache, C.; Passweg, J.R.; Libura, J.; Petrikkos, L.; Seiler, W.O.; Gratwohl, A.; Staehelin, H.B.; Tichelli, A.: Anemia: an indicator for malnutrition in the elderly. Ann Hematol 80 (2001), 295-298 EU07/02

(EU 07/2002, S. 260 ff.) Seiler, W.O., Itin, P., Stähelin, H.B.: Zinkmangel, ein oft verkanntes Problem im Alter

Literatur:    

1. Riordan, J.; Vallee, B.: Structure and function of zinc metalloenzymes; ; In: Prasad, A.; Oberleas, D. : Trace elements in human health and disease. 1- Zinc and cooper. New York, Academic Press, (1976), 227-256

2. Prasad, A.S.: Zinc: an overview. Nutrition. 11 (1995), 93-99

3. Fabris, N.; Mocchegiani, E.: Zinc, human diseases and aging. Aging Clin Exp Res 7 (1995), 77-93

4. Moynahan, E.: Acrodermitis enteropathica: a lethal inherited human zinc-deficiency disorder. Lancet 2 (1974), 399-400

5. Sandstead, H.H.; Henriksen, L.K.; Greger, J.L.; Prasad, A.S.; Good, R.A.: Zinc nutriture in the elderly in relation to taste acuity, immune response, and wound healing. Am J Clin Nutr 36 (1982), 1046-1059

6. Abbasi, A.; Shetty, K.: Zinc: pathophysiological effects, deficiency status and effects of supplementation in elderly persons–an overview of the research. Z Gerontol Geriatr 32, Suppl 1 (1999), 75-79

7. Lansdown, A.B.: Zinc in the healing wound. Lancet 347 (1996), 706-707

8. Iwata, M.; Takebayashi, T.; Ohta, H.; Alcalde, R.E.; Itano, Y.; Matsumura, T.: Zinc accumulation and metallothionein gene expression in the proliferating epidermis during wound healing in mouse skin. Histochem Cell Biol 112 (1999), 283-290

9. Salgueiro, M.J.; Zubillaga, M.; Lysionek, A.; Cremaschi, G.; Goldman, C.G.; Caro, R.; De Paoli, T.; Hager, A.; Weill, R.; Boccio, J.: Zinc status and immune system relationship: a review. Biol Trace Elem Res 76 (2000), 193-205

10. Laditan, A.A.; Ette, S.I.: Plasma zinc and copper levels during the acute phase of protein-energy malnutrition (PEM) and after recovery. Trop Geogr Med 34 (1982), 77-80

11. Constantinidis, J.: The hypothesis of zinc deficiency in the pathogenesis of neurofibrillary tangles. Med Hypoth 35 (1991),319-323

12. Turnlund, J.; Durvin, N.; Costa, F.; Margen, S.: Stable isotope studies of zinc absorption and retension in young and elderly men. J Nutr 116 (1986), 1239-1247

13. Corwin, E.J.: Understanding cytokines. Part I: Physiology and mechanism of action. Biol Res Nurs 2 (2000), 30-40

14. Androsova, L.V.; Kushner, S.G.; Abramova, L.I.; Oleichik, I.V.; Egorova, M.: Interleukin level in endogenous depression. Zh Nevrol Psikhiatr Im S S Korsakova 101 (2001), 45-48

15. Mikova, O.; Yakimova, R.; Bosmans, E.; Kenis, G.; Maes, M.: Increased serum tumor necrosis factor alpha concentrations in major depression and multiple sclerosis. European Neuropsychopharmacology 11 (2001), 203-208

16. Fagiolo, U.; Cosarizza, A.; Sanctacaterina, S.: Increased cytokine production by peripheral blood mononuclear cells from healthy elderly. Ann NY Acad Sci 663 (1992), 490-493

17. Bonnefoy, M.; Coulon, L.; Bienvenu, J.; Boisson, R.C.; Rys, L.: Implication of cytokines in the aggravation of malnutrition and hypercatabolism in elderly patients with severe pressure sores. Age Ageing 24 (1995), 37-42

18. Melchiar, B.; Jandik, P.; Tichy, M.; Malir, F.; Mergancova, J.; Voboril, Z.: Urinary zinc excretion and acute phase response in cancer patients. Clin Investig 72 (1994), 1012-1014

19. Dantzer, R.: Cytokine-induced sickness behavior: where do we stand? Brain Behav Immun 15 (2001), 7-24

20. McWhiter, J.; Pennington, C.: Incidence and recognition of malnurtrition in hospitals. Nutr Hosp 308 (1994), 945-948

21. Potter, J.; Klipstein, K.; Reilly, J.; Robert, M.: The nutritional status and clinical course of acute admissions to a geriatric unit. Age ageing 24 (1995), 131-136

22. Sandström, B.: Dose dependence of zinc and manganese absorption in man. Proc Nutr Soc 51 (1992), 211-218

23. Sandström, B.; Cederblad, A.: Zinc absorption from composite meals. II. Influence of the main protein source. Am J Clin Nutr 33 (1980), 1778-1783

24. Wapnir, R.; Khani, D.; Bayne, M.; Lifshitz, F.: Absorption by the rat ileum: the effect of histidin and other low-molecular-weight ligands. J Nutr 113 (1983), 1434-1442

25. Sandström, B.; Arvidsson, B.; Cederbald, A.; Björn-Rasmussen, E.: Zinc absorption from composite meals. I. The significance of wheat extraction rate, zinc, calcium and protein content in meals based on bread. Am J Clin Nutr 33 (1980), 739-745

26. Monget, A.; Galan, P.; Presiosi, P.; Keller, H.; Bourgeois, C.: Micronutrient status in the elderly people. Internat J Vit Nutr Res 66 (1996), 71-76

27. Stafford, W.; Smith, R.; Lewis, S.; Henery, E.; Stephen, P.: A study of zinc status of elderly institutionalized patients. Age Ageing 17 (1996), 42-48

28. Meertens, L.; Solano, L.; Pena, E.: Zinc status evaluation in an elderly institutionalized population. Arch Latinoam Nutr. 47 (1997), 311-314

29. Morley, J.E.; Silver, A.J.: Nutritional issues in nursing home care. Ann Intern Med 123 (1995), 850-859

30. Worwag, M.; Classen, H.G.; Schumacher, E.: Prevalence of magnesium and zinc deficiencies in nursing home residents in Germany. Magnes Res 12 (1999), 181-189

31. Aggett, P.; Comerford, J.: Zinc and human health. Nutr Rev 53 (1995), 16-22

32. Fraker, P.J.; King, L.: Changes in regulation of lymphopoiesis and myelopoiesis in the zinc-deficient mouse. Nutr Rev 56 (1998), 65-69

33. Fraker, P.J.; King, L.E.; Laakko, T.; Vollmer, T.L.: The dynamic link between the integrity of the immune system and zinc status. J Nutr 130 (2000), 1399S-1406S

34. Souci, S.; Fachmann, W.; Kraut, H.: Die Zusammensetzung der Lebensmittel. Stuttgart, Wissenschaftliche Verlagsgesellschaft mbH (1989).

35. Roth, H.; Kirchgessner, M.: Diagnostik des Zinkmangels. Z Gerontol Geriat 32, Suppl 1 (1999), 55-64

36. Cousins, R.: Absorption, transport and hepatic metabolism of copper and zinc: special reference to metallothionein and ceruloplasmin. Physiol Rev 65 (1985), 238-309

37. Aggett, P.J.; Favier, A.: Zinc. Int J Vitam Nutr Res 63 (1993), 301-307

38. Andrews, M.; Gallagher-Allred, C.: The role of zinc in wound healing. Adv Wound Care 12 (1999), 137-138

39. Maes, M.; De Vos, N.; Demedts, P.; Wauters, A.; Neels, H.: Lower serum zinc in major depression in relation to changes in serum acute phase proteins. J Affect Disord 56 (1999), 189-194

40. Mocchegiani, E.; Muzzioli, M.; Giacconi, R.: Zinc and immunoresistance to infection in aging: new biological tools. Trends Pharmacol Sci. 21 (2000), 205-208

41. Rulon, L.L.; Robertson, J.D.; Lovell, M.A.; Deibel, M.A.; Ehmann, W.D.; Markesber, W.R.: Serum zinc levels and Alzheimer´s disease. Biol Trace Elem Res 75 (2000), 79-85

42. Mitrache, C.; Passweg, J.R.; Libura, J.; Petrikkos, L.; Seiler, W.O.; Gratwohl, A.; Staehelin, H.B.; Tichelli, A.: Anemia: an indicator for malnutrition in the elderly. Ann Hematol 80 (2001), 295-298 EU07/02

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Veröffentlicht: 01.07.2002

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